2 papers
q-bio.PE2020
Lack of evidence for a substantial rate of templated mutagenesis in B cell diversification
Julia Fukuyama, Branden J Olson, Frederick A Matsen
B cell receptor sequences diversify through mutations introduced by purpose-built cellular machinery. A recent paper has concluded that a "templated mutagenesis" process is a major…
q-bio.PE2018
The Bayesian optimist's guide to adaptive immune receptor repertoire analysis
Branden J. Olson, Frederick A. Matsen
Probabilistic modeling is fundamental to the statistical analysis of complex data. In addition to forming a coherent description of the data-generating process, probabilistic model…