3 papers
q-bio.QM2020
Integrative Data Analytic Framework to Enhance Cancer Precision Medicine
Thomas Gaudelet, Noel Malod-Dognin, Natasa Przulj
With the advancement of high-throughput biotechnologies, we increasingly accumulate biomedical data about diseases, especially cancer. There is a need for computational models and…
q-bio.QM2019
Unveiling new disease, pathway, and gene associations via multi-scale neural networks
Thomas Gaudelet, Noel Malod-Dognin, Jon Sanchez-Valle +3
Diseases involve complex processes and modifications to the cellular machinery. The gene expression profile of the affected cells contains characteristic patterns linked to a disea…
q-bio.MN2018
Higher order molecular organisation as a source of biological function
Thomas Gaudelet, Noel Malod-Dognin, Natasa Przulj
Molecular interactions have widely been modelled as networks. The local wiring patterns around molecules in molecular networks are linked with their biological functions. However,…