4 papers
Multidimensional representations in late-life depression: convergence in neuroimaging, cognition, clinical symptomatology and genetics
Junhao Wen, Cynthia H. Y. Fu, Duygu Tosun +22
Late-life depression (LLD) is characterized by considerable heterogeneity in clinical manifestation. Unraveling such heterogeneity would aid in elucidating etiological mechanisms a…
Disentangling Alzheimer's disease neurodegeneration from typical brain aging using machine learning
Gyujoon Hwang, Ahmed Abdulkadir, Guray Erus +18
Neuroimaging biomarkers that distinguish between typical brain aging and Alzheimer's disease (AD) are valuable for determining how much each contributes to cognitive decline. Machi…
MAGIC: Multi-scale Heterogeneity Analysis and Clustering for Brain Diseases
Junhao Wen, Erdem Varol, Ganesh Chand +2
There is a growing amount of clinical, anatomical and functional evidence for the heterogeneous presentation of neuropsychiatric and neurodegenerative diseases such as schizophreni…
Generative discriminative models for multivariate inference and statistical mapping in medical imaging
Erdem Varol, Aristeidis Sotiras, Ke Zeng +1
This paper presents a general framework for obtaining interpretable multivariate discriminative models that allow efficient statistical inference for neuroimage analysis. The frame…