2 papers
physics.bio-ph2020
A critical survey on the kinetic assays of DNA polymerase fidelity from a new theoretical perspective
Qiu-Shi Li, Yao-Gen Shu, Zhong-Can Ou-Yang +1
The high fidelity of DNA polymerase is critical for the faithful replication of genomic DNA. Several approaches were proposed to quantify the fidelity of DNA polymerase. Direct mea…
q-bio.SC2016
Proofreading of DNA Polymerase: a new kinetic model with higher-order terminal effects
Yong-Shun Song, Yao-Gen Shu, Xin Zhou +2
The fidelity of DNA replication by DNA polymerase (DNAP) has long been an important issue in biology. While numerous experiments have revealed details of the molecular structure an…