2 papers
physics.bio-ph2020
A critical survey on the kinetic assays of DNA polymerase fidelity from a new theoretical perspective
Qiu-Shi Li, Yao-Gen Shu, Zhong-Can Ou-Yang +1
The high fidelity of DNA polymerase is critical for the faithful replication of genomic DNA. Several approaches were proposed to quantify the fidelity of DNA polymerase. Direct mea…
cond-mat.stat-mech2019
The template-specific fidelity of DNA replication with high-order neighbor effects: a first-passage approach
Qiu-Shi Li, Pei-Dong Zheng, Yao-Gen Shu +2
DNA replication fidelity is a critical issue in molecular biology. Biochemical experiments have provided key insights on the mechanism of fidelity control by DNAP in the past decad…