17 citations · 27 across the 3 of their papers we have counts for
3 papers
Risperidone response in patients with schizophrenia drives DNA methylation changes in immune and neuronal systems
Ana Lokmer, Charanraj Goud Alladi, Réjane Troudet +9
Background: The choice of efficient antipsychotic therapy for schizophrenia relies on a time-consuming trial-and-error approach, whereas the social and economic burdens of the dise…
PIntMF: Penalized Integrative Matrix Factorization Method for Multi-Omics Data
Morgane Pierre-Jean, Florence Mauger, Jean-François Deleuze +1
It is more and more common to explore the genome at diverse levels and not only at a single omic level. Through integrative statistical methods, omics data have the power to reveal…
High heritability does not imply accurate prediction under the small additive effects hypothesis
Arthur Frouin, Claire Dandine-Roulland, Morgane Pierre-Jean +3
Genome-Wide Association Studies (GWAS) explain only a small fraction of heritability for most complex human phenotypes. Genomic heritability estimates the variance explained by the…