14 citations · 36 across the 7 of their papers we have counts for
7 papers
Evolutionary advantage of cell size control
Spencer Hobson-Gutierrez, Edo Kussell
We analyze the advantage of cell size control strategies in growing populations under mortality constraints. We demonstrate a general advantage of the adder control strategy in the…
Cell cycle heritability and localization phase transition in growing populations
Takashi Nozoe, Edo Kussell
The cell cycle duration is a variable cellular phenotype that underlies long-term population growth and age structures. By analyzing the stationary solutions of a branching process…
Sidechain Dynamics and Protein Folding
E. Kussell, J. Shimada, E. I. Shakhnovich
The processes by which protein sidechains reach equilibrium during a folding reaction are investigated using both lattice and all-atom simulations. We find that rates of sidechain…
Excluded Volume in Protein Sidechain Packing
Edo Kussell, Jun Shimada, Eugene I. Shakhnovich
To examine the relationship between sidechain geometry and sidechain packing, we use an all-atom Monte Carlo simulation to sample the large space of sidechain conformations. We stu…
The Folding Thermodynamics and Kinetics of Crambin Using an All-Atom Monte Carlo Simulation
J. Shimada, E. L. Kussell, E. I. Shakhnovich
We present a novel Monte Carlo simulation of protein folding, in which all heavy atoms are represented as interacting hard spheres. This model includes all degrees of freedom relev…
An Analytical Approach to the Protein Designability Problem
Edo L. Kussell, Eugene I. Shakhnovich
We present an analytical method for determining the designability of protein structures. We apply our method to the case of two-dimensional lattice structures, and give a systemati…