155 citations · 393 across the 20 of their papers we have counts for
20 papers
Intracranial EEG structure-function coupling predicts surgical outcomes in focal epilepsy
Nishant Sinha, John S. Duncan, Beate Diehl +9
Alterations to structural and functional brain networks have been reported across many neurological conditions. However, the relationship between structure and function -- their co…
Volumetric and structural connectivity abnormalities co-localise in TLE
Jonathan J. Horsley, Gabrielle M. Schroeder, Rhys H. Thomas +6
Patients with temporal lobe epilepsy (TLE) exhibit both volumetric and structural connectivity abnormalities relative to healthy controls. How these abnormalities inter-relate and…
Chronic iEEG recordings and interictal spike rate reveal multiscale temporal modulations in seizure states
Gabrielle M. Schroeder, Philippa J. Karoly, Matias Maturana +4
Background and Objectives: Many biological processes are modulated by rhythms on circadian and multidien timescales. In focal epilepsy, various seizure features, such as spread and…
Seizure pathways and seizure durations can vary independently within individual patients with focal epilepsy
Gabrielle M. Schroeder, Fahmida A. Chowdhury, Mark J. Cook +5
A seizure's electrographic dynamics are characterised by its spatiotemporal evolution, also termed dynamical "pathway" and the time it takes to complete that pathway, which results…
Long-term changes in functional connectivity predict responses to intracranial stimulation of the human brain
Christoforos Papasavvas, Peter Neal Taylor, Yujiang Wang
Targeted electrical stimulation of the brain perturbs neural networks and modulates their rhythmic activity both at the site of stimulation and at remote brain regions. Understandi…
Normative brain mapping of interictal intracranial EEG to localise epileptogenic tissue
Peter N Taylor, Christoforos A Papasavvas, Thomas W Owen +11
The identification of abnormal electrographic activity is important in a wide range of neurological disorders, including epilepsy for localising epileptogenic tissue. However, this…
Fluctuations in EEG band power at subject-specific timescales over minutes to days explain changes in seizure evolutions
Mariella Panagiotopoulou, Christoforos A Papasavvas, Gabrielle M Schroeder +3
Epilepsy is recognised as a dynamic disease, where both seizure susceptibility and seizure characteristics themselves change over time. Specifically, we recently quantified the var…
Focal to bilateral tonic-clonic seizures are associated with widespread network abnormality in temporal lobe epilepsy
Nishant Sinha, Natalie Peternell, Gabrielle M. Schroeder +6
Objective: To identify if whole-brain structural network alterations in patients with temporal lobe epilepsy (TLE) and focal to bilateral tonic-clonic seizures (FBTCS) differ from…
Multivariate white matter alterations are associated with epilepsy duration
Tom W. Owen, Jane de Tisi, Sjoerd B. Vos +4
Previous studies investigating associations between white matter alterations and duration of temporal lobe epilepsy (TLE) have shown differing results, and were typically limited t…
Band power modulation through intracranial EEG stimulation and its cross-session consistency
Christoforos A Papasavvas, Gabrielle M Schroeder, Beate Diehl +3
Background: Direct electrical stimulation of the brain through intracranial electrodes is currently used to probe the epileptic brain as part of pre-surgical evaluation, and it is…
Independent components of human brain morphology
Yujiang Wang, Tobias Ludwig, Bethany Little +7
Quantification of brain morphology has become an important cornerstone in understanding brain structure. Measures of cortical morphology such as thickness and surface area are freq…
Reliability and comparability of human brain structural covariance networks
Jona Carmon, Jil Heege, Joe H Necus +5
Structural covariance analysis is a widely used structural MRI analysis method which characterises the co-relations of morphology between brain regions over a group of subjects. To…
Interictal intracranial EEG for predicting surgical success: the importance of space and time
Yujiang Wang, Nishant Sinha, Gabrielle M. Schroeder +8
Predicting post-operative seizure freedom using functional correlation networks derived from interictal intracranial EEG has shown some success. However, there are important challe…
Carbogen inhalation during Non-Convulsive Status Epilepticus: A quantitative analysis of EEG recordings
Sriharsha Ramaraju, Simon Reichert, Yujiang Wang +2
Objective: To quantify the effect of inhaled 5% carbon-dioxide/95% oxygen on EEG recordings from patients in non-convulsive status epilepticus (NCSE). Methods: Five children of mix…
Personalised network modelling in epilepsy
Yujiang Wang, Gabrielle Marie Schroeder, Nishant Sinha +1
Epilepsy is a disorder characterised by spontaneous, recurrent seizures. Both local and network abnormalities have been associated with epilepsy, and the exact processes generating…
Computer modelling of connectivity change suggests epileptogenesis mechanisms in idiopathic generalised epilepsy
Nishant Sinha, Yujiang Wang, Justin Dauwels +4
Patients with idiopathic generalised epilepsy (IGE) typically have normal conventional magnetic resonance imaging (MRI), hence MRI based diagnosis is challenging. Anatomical abnorm…
Universality in human cortical folding across lobes of individual brains
Yujiang Wang, Joe Necus, Luis Peraza Rodriguez +2
Background: We have previously demonstrated that cortical folding across mammalian species follows a universal scaling law that can be derived from a simple theoretical model. The…
The impact of epilepsy surgery on the structural connectome and its relation to outcome
Peter N Taylor, Nishant Sinha, Yujiang Wang +6
Temporal lobe surgical resection brings seizure remission in up to 80% of patients, with long-term complete seizure freedom in 41%. However, it is unclear how surgery impacts on th…
Understanding Epileptiform After-Discharges as Rhythmic Oscillatory Transients
Gerold Baier, Peter N Taylor, Yujiang Wang
Electro-cortical activity in patients with epilepsy may show abnormal rhythmic transients in response to stimulation. Even when using the same stimulation parameters in the same pa…
Mechanisms underlying different onset patterns of focal seizures
Yujiang Wang, Andrew J Trevelyan, Antonio Valentin +3
Focal seizures are episodes of pathological brain activity that appear to arise from a localised area of the brain. The onset patterns of focal seizure activity have been studied i…