155 citations · 178 across the 14 of their papers we have counts for
13 papers · 1 filter
Open diffusion MRI and connectivity data for epilepsy and surgery: The IDEAS II release
Peter N. Taylor, Gerard Hall, Jonathan Horsley +7
Epileptic seizures are generated in cerebral networks that propagate ictal and interictal activity. The structure of cerebral networks underpinning epileptic activity can be inferr…
Combined impact of grey and superficial white matter abnormalities: implications for epilepsy surgery
Csaba Kozma, Jonathan Horsley, Gerard Hall +9
Drug-resistant focal epilepsy is associated with abnormalities in the brain in both grey matter (GM) and superficial white matter (SWM). However, it is unknown if both types of abn…
Seizure freedom after surgical resection of diffusion-weighted MRI abnormalities
Jonathan Horsley, Gerard Hall, Callum Simpson +10
Importance: Many individuals with drug-resistant epilepsy continue to have seizures after resective surgery. Accurate identification of focal brain abnormalities is essential for s…
The Imaging Database for Epilepsy And Surgery (IDEAS)
Peter N. Taylor, Yujiang Wang, Callum Simpson +12
Magnetic resonance imaging (MRI) is a crucial tool to identify brain abnormalities in a wide range of neurological disorders. In focal epilepsy MRI is used to identify structural c…
Complementary structural and functional abnormalities to localise epileptogenic tissue
Jonathan J Horsley, Rhys H Thomas, Fahmida A Chowdhury +10
When investigating suitability for surgery, people with drug-refractory focal epilepsy may have intracranial EEG (iEEG) electrodes implanted to localise seizure onset. Diffusion-we…
Effects of anterior temporal lobe resection on cortical morphology
Karoline Leiberg, Jane de Tisi, John S Duncan +6
Anterior temporal lobe resection (ATLR) is a surgical procedure to treat drug-resistant temporal lobe epilepsy (TLE). Resection may involve large amounts of cortical tissue. Here,…
Intracranial EEG structure-function coupling predicts surgical outcomes in focal epilepsy
Nishant Sinha, John S. Duncan, Beate Diehl +9
Alterations to structural and functional brain networks have been reported across many neurological conditions. However, the relationship between structure and function -- their co…
Volumetric and structural connectivity abnormalities co-localise in TLE
Jonathan J. Horsley, Gabrielle M. Schroeder, Rhys H. Thomas +6
Patients with temporal lobe epilepsy (TLE) exhibit both volumetric and structural connectivity abnormalities relative to healthy controls. How these abnormalities inter-relate and…
Normative brain mapping of interictal intracranial EEG to localise epileptogenic tissue
Peter N Taylor, Christoforos A Papasavvas, Thomas W Owen +11
The identification of abnormal electrographic activity is important in a wide range of neurological disorders, including epilepsy for localising epileptogenic tissue. However, this…
Focal to bilateral tonic-clonic seizures are associated with widespread network abnormality in temporal lobe epilepsy
Nishant Sinha, Natalie Peternell, Gabrielle M. Schroeder +6
Objective: To identify if whole-brain structural network alterations in patients with temporal lobe epilepsy (TLE) and focal to bilateral tonic-clonic seizures (FBTCS) differ from…
Multivariate white matter alterations are associated with epilepsy duration
Tom W. Owen, Jane de Tisi, Sjoerd B. Vos +4
Previous studies investigating associations between white matter alterations and duration of temporal lobe epilepsy (TLE) have shown differing results, and were typically limited t…
Independent components of human brain morphology
Yujiang Wang, Tobias Ludwig, Bethany Little +7
Quantification of brain morphology has become an important cornerstone in understanding brain structure. Measures of cortical morphology such as thickness and surface area are freq…
The impact of epilepsy surgery on the structural connectome and its relation to outcome
Peter N Taylor, Nishant Sinha, Yujiang Wang +6
Temporal lobe surgical resection brings seizure remission in up to 80% of patients, with long-term complete seizure freedom in 41%. However, it is unclear how surgery impacts on th…