473 citations · 654 across the 4 of their papers we have counts for
4 papers
Deciphering antibody affinity maturation with language models and weakly supervised learning
Jeffrey A. Ruffolo, Jeffrey J. Gray, Jeremias Sulam
In response to pathogens, the adaptive immune system generates specific antibodies that bind and neutralize foreign antigens. Understanding the composition of an individual's immun…
Advances to tackle backbone flexibility in protein docking
Ameya Harmalkar, Jeffrey J. Gray
Computational docking methods can provide structural models of protein-protein complexes, but protein backbone flexibility upon association often thwarts accurate predictions. In r…
Deep Learning in Protein Structural Modeling and Design
Wenhao Gao, Sai Pooja Mahajan, Jeremias Sulam +1
Deep learning is catalyzing a scientific revolution fueled by big data, accessible toolkits, and powerful computational resources, impacting many fields including protein structura…
Serverification of Molecular Modeling Applications: the Rosetta Online Server that Includes Everyone (ROSIE)
Sergey Lyskov, Fang-Chieh Chou, Shane Ó Conchúir +14
The Rosetta molecular modeling software package provides experimentally tested and rapidly evolving tools for the 3D structure prediction and high-resolution design of proteins, nu…