67 citations · 87 across the 6 of their papers we have counts for
6 papers
A design specification for Critical Illness Digital Twins to cure sepsis: responding to the National Academies of Sciences, Engineering and Medicine Report: Foundational Research Gaps and Future Directions for Digital Twins
Gary An, Chase Cockrell
On December 15, 2023, The National Academies of Sciences, Engineering and Medicine (NASEM) released a report entitled: Foundational Research Gaps and Future Directions for Digital…
Generating synthetic multi-dimensional molecular-mediator time series data for artificial intelligence-based disease trajectory forecasting and drug development digital twins: Considerations
Gary An, Chase Cockrell
The use of synthetic data is recognized as a crucial step in the development of neural network-based Artificial Intelligence (AI) systems. While the methods for generating syntheti…
Facilitating automated conversion of scientific knowledge into scientific simulation models with the Machine Assisted Generation, Calibration, and Comparison (MAGCC) Framework
Chase Cockrell, Scott Christley, Gary An
The Machine Assisted Generation, Comparison, and Calibration (MAGCC) framework provides machine assistance and automation of recurrent crucial steps and processes in the developmen…
Artificial neural networks for disease trajectory prediction in the context of sepsis
Dale Larie, Gary An, Chase Cockrell
The disease trajectory for clinical sepsis, in terms of temporal cytokine and phenotypic dynamics, can be interpreted as a random dynamical system. The ability to make accurate pre…
Precision medicine as a control problem: Using simulation and deep reinforcement learning to discover adaptive, personalized multi-cytokine therapy for sepsis
Brenden K. Petersen, Jiachen Yang, Will S. Grathwohl +4
Sepsis is a life-threatening condition affecting one million people per year in the US in which dysregulation of the body's own immune system causes damage to its tissues, resultin…
Lithium isotopes within the ab intio no-core full configuration approach
Chase Cockrell, James P. Vary, Pieter Maris
We perform no-core full configuration calculations for the Lithium isotopes, 6Li, 7Li, and 8Li with the realistic nucleon-nucleon interaction JISP16. We obtain a set of observables…