activity
20182021
most citedPhase Imaging with Computational Specificity (PICS) for measuring dry mass changes in sub-cellular compartments

163 citations · 285 across the 7 of their papers we have counts for

collaborators

7 papers

physics.optics2021★ 65 cited

Artificial confocal microscopy for deep label-free imaging

Xi Chen, Mikhail E. Kandel, Shenghua He +8

Widefield microscopy methods applied to optically thick specimens are faced with reduced contrast due to spatial crosstalk, in which the signal at each point is the result of a sup…

physics.optics2021★ 10 cited

Synthetic aperture interference light (SAIL) microscopy for high-throughput label-free imaging

Chenfei Hu, Mikhail E. Kandel, Young Jae Lee +1

Quantitative phase imaging (QPI) is a valuable label-free modality that has gained significant interest due to its wide potentials, from basic biology to clinical applications. Mos…

eess.IV2020★ 3 cited

Multiscale assay of unlabeled neurite dynamics using phase imaging with computational specificity (PICS)

Mikhail E. Kandel, Eunjae Kim, Young Jae Lee +3

Primary neuronal cultures have been widely used to study neuronal morphology, neurophysiology, neurodegenerative processes, and molecular mechanism of synaptic plasticity underlyin…

physics.optics2020★ 1 cited

Wolf phase tomography (WPT) of transparent structures using partially coherent illumination

Xi Chen, Mikhail E. Kandel, Chenfei Hu +2

Diffraction tomography using coherent holographic imaging has been proposed by Emil Wolf in 1969 to extract 3D information from transparent, inhomogeneous objects. At the same time…

eess.IV2020★ 163 cited

Phase Imaging with Computational Specificity (PICS) for measuring dry mass changes in sub-cellular compartments

Mikhail E. Kandel, Yuchen R. He, Young Jae Lee +7

Due to its specificity, fluorescence microscopy (FM) has become a quintessential imaging tool in cell biology. However, photobleaching, phototoxicity, and related artifacts continu…

q-bio.QM2020★ 16 cited

Quantifying myelin in brain tissue using color spatial light interference microscopy (cSLIM)

Michael Fanous, Megan P. Caputo, Young Jae Lee +7

Deficient myelination of the brain is associated with neurodevelopmental delays, particularly in high-risk infants, such as those born small in relation to their gestational age (S…

physics.optics2018★ 27 cited

Magnified Image Spatial Spectrum (MISS) microscopy for nanometer and millisecond scale label-free imaging

Hassaan Majeed, Lihong Ma, Young Jae Lee +5

Label-free imaging of rapidly moving, sub-diffraction sized structures has important applications in both biology and material science, as it removes the limitations associated wit…