62 citations · 177 across the 6 of their papers we have counts for
6 papers
AlphaFold2 for protein structure prediction: Best practices and critical analyses
Ragousandirane Radjasandirane, Alexandre G. de Brevern
AlphaFold2 (AF2) has emerged in recent years as a groundbreaking innovation that has revolutionized several scientific fields, in particular structural biology, drug design and the…
Investigating the Product Profiles and Structural Relationships of New Levansucrases with Conventional and Non-Conventional Substrates
Andrea Hill, Salwa Karboune, Tarun Narwani +1
The synthesis of complex oligosaccharides is desired for their potential as prebiotics, and their role in the pharmaceutical and food industry. Levansucrase (LS, EC 2.4.1.10), a fr…
Investigation of the impact of PTMs on the protein backbone conformation
Pierrick Craveur, Tarun Narwani, Joseph Rebehmed +1
Post-Translational Modifications (PTMs) are known to play a critical role in the regulation of the protein functions. Their impact on protein structures, and their link to disorder…
In silico prediction of protein flexibility with local structure approach
Tarun Narwani, Catherine Etchebest, Pierrick Craveur +6
Flexibility is an intrinsic essential feature of protein structures, directly linked to their functions. To this day, most of the prediction methods use the crystallographic data (…
Same but not alike: Structure, flexibility and energetics of domains in multi-domain proteins are influenced by the presence of other domains
Sneha Vishwanath, Alexandre De Brevern, Narayanaswamy Srinivasan
The majority of the proteins encoded in the genomes of eukaryotes contain more than one domain. Reasons for high prevalence of multi-domain proteins in various organisms have been…
Global analysis of VHHs framework regions with a structural alphabet
Floriane Noël, Alain Malpertuy, Alexandre De Brevern
The VHHs are antigen-binding region/domain of camelid heavy chain antibodies (HCAb). They have many interesting biotechnological and biomedical properties due to their small size,…