100 citations · 176 across the 15 of their papers we have counts for
3 papers · 1 filter
Ranking-based Convolutional Neural Network Models for Peptide-MHC Binding Prediction
Ziqi Chen, Martin Renqiang Min, Xia Ning
T-cell receptors can recognize foreign peptides bound to major histocompatibility complex (MHC) class-I proteins, and thus trigger the adaptive immune response. Therefore, identify…
A Deep Generative Model for Molecule Optimization via One Fragment Modification
Ziqi Chen, Martin Renqiang Min, Srinivasan Parthasarathy +1
Molecule optimization is a critical step in drug development to improve desired properties of drug candidates through chemical modification. We developed a novel deep generative mo…
Network reinforcement driven drug repurposing for COVID-19 by exploiting disease-gene-drug associations
Yonghyun Nam, Jae-Seung Yun, Seung Mi Lee +7
Currently, the number of patients with COVID-19 has significantly increased. Thus, there is an urgent need for developing treatments for COVID-19. Drug repurposing, which is the pr…