133 citations · 199 across the 3 of their papers we have counts for
3 papers
Survival of the densest accounts for the expansion of mitochondrial mutations in ageing
Ferdinando Insalata, Hanne Hoitzing, Juvid Aryaman +1
The expansion of deleted mitochondrial DNA (mtDNA) molecules has been linked to ageing, particularly in skeletal muscle fibres; its mechanism has remained unclear for three decades…
Mitochondrial network state scales mtDNA genetic dynamics
Juvid Aryaman, Charlotte Bowles, Nick S. Jones +1
Mitochondrial DNA (mtDNA) mutations cause severe congenital diseases but may also be associated with healthy aging. MtDNA is stochastically replicated and degraded, and exists with…
Mitochondrial heterogeneity
Juvid Aryaman, Iain G. Johnston, Nick S. Jones
Cell-to-cell heterogeneity drives a range of (patho)physiologically important phenomena, such as cell fate and chemotherapeutic resistance. The role of metabolism, and particularly…