56 citations · 76 across the 3 of their papers we have counts for
4 papers · 1 filter
Nigral diffusivity, but not free water, correlates with iron content in Parkinson's disease
Jason Langley, Daniel E. Huddleston, Xiaoping P. Hu
The loss of melanized neurons in the substantia nigra pars compacta is a primary feature in Parkinson's disease (PD). Iron deposition occurs in conjunction with this loss. Loss of…
Impact of locus coeruleus and its projections on memory and aging
Jason Langley, Sana Hussain, Daniel E. Huddleston +2
Introduction: Locus coeruleus (LC) is the primary source of norepinephrine to the brain and its efferent projections innervate many brain regions, including the thalamus. LC degrad…
Multimodal assessment of nigrosomal degeneration in Parkinson's disease
Jason Langley, Daniel E. Huddleston, Bruce Crosson +3
Background: Approximately forty percent of all dopaminergic neurons in SNpc are located in five dense neuronal clusters, named nigrosomes. T2- or T2*-weighted images are used to de…
Characterization of Age-related Microstructural Changes in Locus Coeruleus and Substantia Nigra Pars Compacta
Jason Langley, Sana Hussain, Justino J. Flores +2
Locus coeruleus (LC) and substantia nigra pars compacta (SNpc) degrade with normal aging, but not much is known regarding how these changes manifest in MRI images, or whether these…