20 citations · 41 across the 9 of their papers we have counts for
9 papers
Designing experimental conditions to use the Lotka-Volterra model to infer tumor cell line interaction types
Heyrim Cho, Allison L. Lewis, Kathleen M. Storey +1
The Lotka-Volterra model is widely used to model interactions between two species. Here, we generate synthetic data mimicking competitive, mutualistic and antagonistic interactions…
Utilizing gradient approximations to optimize data selection protocols for tumor growth model calibration
Allison L. Lewis, Kathleen M. Storey, Heyrim Cho +1
The use of mathematical models to make predictions about tumor growth and response to treatment has become increasingly more prevalent in the clinical setting. The level of complex…
Effective dose fractionation schemes of radiotherapy for prostate cancer
Jose Alvarez, Kathleen M. Storey, Pavitra Kannan +1
Radiation therapy has remained as one of the main cancer treatment modalities and a highly cost-effective single modality treatment of cancer care. Typical regimens for fractionate…
Application of adaptive ANOVA and reduced basis methods to the stochastic Stokes-Brinkman problem
Kevin Williamson, Heyrim Cho, Bedřich Sousedík
The Stokes-Brinkman equations model fluid flow in highly heterogeneous porous media. In this paper, we consider the numerical solution of the Stokes-Brinkman equations with stochas…
Bayesian information-theoretic calibration of patient-specific radiotherapy sensitivity parameters for informing effective scanning protocols in cancer
Heyrim Cho, Allison L. Lewis, Kathleen M. Storey
With new advancements in technology, it is now possible to collect data for a variety of different metrics describing tumor growth, including tumor volume, composition, and vascula…
Study of dose-dependent combination immunotherapy using engineered T cells and IL-2 in cervical cancer
Heyrim Cho, Zuping Wang, Doron Levy
Adoptive T cell based immunotherapy is gaining significant traction in cancer treatment. Despite its limited success, so far, in treating solid cancers, it is increasingly successf…
Modeling continuous levels of resistance to multidrug therapy in cancer
Heyrim Cho, Doron Levy
Multidrug resistance consists of a series of genetic and epigenetic alternations that involve multifactorial and complex processes, which are a challenge to successful cancer treat…
The Impact of Competition Between Cancer Cells and Healthy Cells on Optimal Drug Delivery
Heyrim Cho, Doron Levy
Cell competition is recognized to be instrumental to the dynamics and structure of the tumor-host interface in invasive cancers. In mild competition scenarios, the healthy tissue a…
An adaptive reduced basis collocation method based on PCM ANOVA decomposition for anisotropic stochastic PDEs
Heyrim Cho, Howard C. Elman
The combination of reduced basis and collocation methods enables efficient and accurate evaluation of the solutions to parameterized PDEs. In this paper, we study the stochastic co…