482 citations · 812 across the 26 of their papers we have counts for
26 papers
Controlling Defects and Probing Dynamics in Active Nematics with Deep Reinforcement Learning
Russ Islam, Kyogo Kawaguchi, Yuto Ashida
Topological defects govern much of the flow behavior and orientational order in active nematics, making their control relevant for active matter physics, smart materials, and micro…
Beyond local detailed balance: Microscopic rates reshape nonequilibrium phase behavior
Takahiro Kanazawa, Kyogo Kawaguchi, Kyosuke Adachi
Local detailed balance (LDB) is a central guiding principle for modeling nonequilibrium stochastic dynamics, yet it only constrains the ratio of forward and backward transition rat…
Hydrodynamic origins of symmetric swimming strategies
Takahiro Kanazawa, Kenta Ishimoto, Kyogo Kawaguchi
Efficient locomotion is important for the evolution of complex life, yet the physical principles selecting specific swimming strokes often remain entangled with biological constrai…
Unifying Theories in High-Dimensional Biology: Approaches, Challenges and Opportunities
Marianne Bauer, Akshit Goyal, Sidhartha Goyal +19
Across biological subdisciplines, the last decade has seen an explosion of high-dimensional datasets, including datasets for cells, species, immune systems, neurons and behaviour.…
Dynamical phase transitions in single particle Brownian motion without drift
Takahiro Kanazawa, Kyogo Kawaguchi, Kyosuke Adachi
Dynamical phase transitions (DPTs) arise from qualitative changes in the long-time behavior of stochastic trajectories, often observed in systems with kinetic constraints or driven…
Universality in the dynamical phase transitions of Brownian motion
Takahiro Kanazawa, Kyogo Kawaguchi, Kyosuke Adachi
We study the dynamical phase transitions (DPTs) appearing for a single Brownian particle without drift. We first explore how first-order DPTs in large deviations can be found even…
Hermitian and non-Hermitian topology in active matter
Kazuki Sone, Kazuki Yokomizo, Kyogo Kawaguchi +1
Self-propulsion is a quintessential aspect of biological systems, which can induce nonequilibrium phenomena that have no counterparts in passive systems. Motivated by biophysical i…
Experimental identification of force, velocity, and nematic order relationships in active nematic cell monolayers
Masahito Uwamichi, He Li, Zihui Zhao +4
Cell alignment often forms nematic order, which can lead to anomalous collective cell flow due to the so-called active force. Although it is appreciated that cell migration is driv…
Predicting heteropolymer interactions: demixing and hypermixing of disordered protein sequences
Kyosuke Adachi, Kyogo Kawaguchi
Cells contain multiple condensates which spontaneously form due to the heterotypic interactions between their components. Although the proteins and disordered region sequences that…
Activity-induced ferromagnetism in one-dimensional quantum many-body systems
Kazuaki Takasan, Kyosuke Adachi, Kyogo Kawaguchi
We study a non-Hermitian quantum many-body model in one dimension analogous to the Vicsek model or active spin models, and investigate its quantum phase transitions. The model cons…
Universality of active and passive phase separation in a lattice model
Kyosuke Adachi, Kyogo Kawaguchi
The motility-induced phase separation (MIPS) is the spontaneous aggregation of active particles, while equilibrium phase separation (EPS) is thermodynamically driven by attractive…
Chirality-driven edge flow and non-Hermitian topology in active nematic cells
Lisa Yamauchi, Tomoya Hayata, Masahito Uwamichi +2
Many of the biological phenomena involve collective dynamics driven by self-propelled motion and nonequilibrium force (i.e., activity) that result in features unexpected from equil…
Activity-induced phase transition in a quantum many-body system
Kyosuke Adachi, Kazuaki Takasan, Kyogo Kawaguchi
A crowd of nonequilibrium entities can show phase transition behaviors that are prohibited in conventional equilibrium setups. An interesting question is whether similar activity-d…
Surface wetting by kinetic control of liquid-liquid phase separation
Kyosuke Adachi, Kyogo Kawaguchi
Motivated by the observations of intracellular phase separations and the wetting of cell membranes by protein droplets, we study the nonequilibrium surface wetting by Monte Carlo s…
Chromatin state switching in a polymer model with mark-conformation coupling
Kyosuke Adachi, Kyogo Kawaguchi
We investigate the phase transition properties of the polymer-Potts model, a chain composed of monomers with magnetic degrees of freedom, with the motivation to study the conformat…
Universal voter model emergence in genetically labeled homeostatic tissues
Hiroki Yamaguchi, Kyogo Kawaguchi
Recent experiments in adult mammalian tissues have found scaling relations of the voter model in the dynamics of the genetically labeled population of stem cells. Yet, the reason f…
Nonequilibrium fluctuation response relation in a time scale separated system
Shou-Wen Wang, Kyogo Kawaguchi, Shin-ichi Sasa +1
We present a theoretical framework to analyze the violation of fluctuation-response relation (FRR) for any observable from a finite Markov system with two well-separated time scale…
Unattainability of Carnot efficiency in thermal motors: Coarse-graining and entropy production of Feynman-Smoluchowski ratchet
Yohei Nakayama, Kyogo Kawaguchi, Naoko Nakagawa
We revisit and analyze the thermodynamic efficiency of the Feynman-Smoluchowski (FS) ratchet, a classical thought experiment describing an autonomous heat-work converter. Starting…
Topological defect launches 3D mound in the active nematic sheet of neural progenitors
Kyogo Kawaguchi, Ryoichiro Kageyama, Masaki Sano
Cultured stem cells have become a standard platform not only for regenerative medicine and developmental biology but also for biophysical studies. Yet, the characterization of cult…
Dynamical Crossover in a Stochastic Model of Cell Fate Decision
Hiroki Yamaguchi, Kyogo Kawaguchi, Takahiro Sagawa
We study the asymptotic behaviors of stochastic cell fate decision between proliferation and differentiation. We propose a model of a self-replicating Langevin system, where cells…
Entropy production of nano systems with timescale separation
Shou-Wen Wang, Kyogo Kawaguchi, Shin-ichi Sasa +1
Energy flow in bio-molecular motors and machines are vital to their function. Yet experimental observations are often limited to a small subset of variables that participate in ene…
Usefulness of effective field theory for boosted Higgs production
S. Dawson, I. M. Lewis, Mao Zeng
The Higgs + jet channel at the LHC is sensitive to the effects of new physics both in the total rate and in the transverse momentum distribution at high p_T. We examine the product…
Nonequilibrium dissipation-free transport in F1-ATPase and the thermodynamic role of asymmetric allosterism
Kyogo Kawaguchi, Shin-ichi Sasa, Takahiro Sagawa
F1-ATPase (or F1), the highly-efficient and reversible biochemical engine, has motivated physicists as well as biologists to imagine the design principles governing machines in the…
Invariance of Steady State Thermodynamics between Different Scales of Description
Yohei Nakayama, Kyogo Kawaguchi
By considering general Markov stochastic dynamics and its coarse-graining, we study the framework of stochastic thermodynamics for the original and reduced descriptions correspondi…