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Topology-Aware Training and Spatial Diagnostics for Fiber Bundle Segmentation in Tracer Histology
Joselyn Romero Avila, Kyriaki-Margarita Bintsi, Ermias Habte +3
Anatomic tracer studies reveal how axon bundles project from an injection site, branch into smaller groups of axons, and course through the brain to reach their destinations. Histo…
Tractography-Driven Synthetic Data Generation for Fiber Bundle Segmentation in Tracer Histology
Kyriaki-Margarita Bintsi, Sparsh Makharia, Yaël Balbastre +4
Diffusion MRI (dMRI) tractography enables non-invasive reconstruction of white-matter pathways, but its accuracy is fundamentally limited by indirect, low-resolution measurements o…
Fully Automated Segmentation of Fiber Bundles in Anatomic Tracing Data
Kyriaki-Margarita Bintsi, Yaël Balbastre, Jingjing Wu +3
Anatomic tracer studies are critical for validating and improving diffusion MRI (dMRI) tractography. However, large-scale analysis of data from such studies is hampered by the labo…
Joint inference on structural and diffusion MRI for sequence-adaptive Bayesian segmentation of thalamic nuclei with probabilistic atlases
Juan Eugenio Iglesias, Koen Van Leemput, Polina Golland +1
Segmentation of structural and diffusion MRI (sMRI/dMRI) is usually performed independently in neuroimaging pipelines. However, some brain structures (e.g., globus pallidus, thalam…