6 papers
Robust Real-time Computing with Chemical Reaction Networks
Willem Fletcher, Titus H. Klinge, James I. Lathrop +2
Recent research into analog computing has introduced new notions of computing real numbers. Huang, Klinge, Lathrop, Li, and Lutz defined a notion of computing real numbers in real-…
Modulated Signals in Chemical Reaction Networks
Titus H. Klinge, James I. Lathrop
Electrical engineering and molecular programming share many of the same mathematical foundations. In this paper, we show how to send multiple signals through a single pair of chemi…
Robust Chemical Circuits
Samuel J. Ellis, Titus H. Klinge, James I. Lathrop
We introduce a new motif for constructing robust digital logic circuits using input/output chemical reaction networks. These chemical circuits robustly handle perturbations in inpu…
Real-Time Computability of Real Numbers by Chemical Reaction Networks
Xiang Huang, Titus H. Klinge, James I. Lathrop +2
We explore the class of real numbers that are computed in real time by deterministic chemical reaction networks that are integral in the sense that all their reaction rate constant…
Runtime Fault Detection in Programmed Molecular Systems
Samuel J. Ellis, Titus H. Klinge, James I. Lathrop +4
Watchdog timers are devices that are commonly used to monitor the health of safety-critical hardware and software systems. Their primary function is to raise an alarm if the monito…
Robust Biomolecular Finite Automata
Titus H. Klinge, James I. Lathrop, Jack H. Lutz
We present a uniform method for translating an arbitrary nondeterministic finite automaton (NFA) into a deterministic mass action input/output chemical reaction network (I/O CRN) t…