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physics.app-ph2022★ 12 cited
Modular microfluidic platform for solubility measurement, nucleation statistics and polymorph screening of active pharmaceutical ingredients: Irbesartan, Rimonabant, Aripiprazole and Sulfathiazole
Mathilde Lambert, Romain Grossier, Mehdi Lagaize +5
Drug efficacy strongly relies on the solid state of the active pharmaceutical ingredient. Classical solid-state screening methods involve different solvent compositions and supersa…
physics.app-ph2020
Microfluidics platform for polymorph screening directly from powder
Guillem Peybernès, Romain Grossier, Frédéric Villard +3
We describe a microfluidic platform for solid phase screening using extremely small quantities of raw materials. Based on our previous setup for solubility measurement that generat…