1 citations · 1 across the 4 of their papers we have counts for
3 papers · 1 filter
Augmenting control arms with Real-World Data for cancer trials: Hybrid control arm methods and considerations
W. Katherine Tan, Brian D. Segal, Melissa D. Curtis +9
Randomized controlled trials (RCTs) are the gold standard for assessing drug safety and efficacy. However, RCTs have some drawbacks which have led to the use of single-arm studies…
A Survival Mediation Model with Bayesian Model Averaging
Jie Zhou, Xun Jiang, H. Amy Xia +2
Determining the extent to which a patient is benefiting from cancer therapy is challenging. Criteria for quantifying the extent of "tumor response" observed within a few cycles of…
Statistical design considerations for trials that study multiple indications
Alexander M. Kaizer, Joseph S. Koopmeiners, Nan Chen +1
Breakthroughs in cancer biology have defined new research programs emphasizing the development of therapies that target specific pathways in tumor cells. Innovations in clinical tr…