activity
20202022
most citedHydrophobic interaction determines docking affinity of SARS CoV 2 variants with antibodies

2 citations · 2 across the 5 of their papers we have counts for

collaborators

5 papers

q-bio.BM2022

The low-entropy hydration shell at the binding site of spike RBD determines the contagiousness of SARS-CoV-2 variants

Lin Yang, Shuai Guo, Chengyu Houc +9

The infectivity of SARS-CoV-2 depends on the binding affinity of the receptor-binding domain (RBD) of the spike protein with the angiotensin converting enzyme 2 (ACE2) receptor. Th…

q-bio.BM2022

Space Layout of Low-entropy Hydration Shells Guides Protein Binding

Lin Yang, Shuai Guo, Chengyu Hou +9

Protein-protein binding enables orderly and lawful biological self-organization, and is therefore considered a miracle of nature. Protein-protein binding is steered by electrostati…

q-bio.BM20212 cited

Hydrophobic interaction determines docking affinity of SARS CoV 2 variants with antibodies

Jiacheng Li, Chengyu Hou, Menghao Wang +10

Preliminary epidemiologic, phylogenetic and clinical findings suggest that several novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have increased transm…

q-bio.BM2020

The role of hydrophobic interactions in folding of -sheets

Jiacheng Li, Xiaoliang Ma, Hongchi Zhang +8

Exploring the protein-folding problem has been a long-standing challenge in molecular biology. Protein folding is highly dependent on folding of secondary structures as the way to…

q-bio.BM2020

A hydrophobic-interaction-based mechanism trigger docking between the SARS CoV 2 spike and angiotensin-converting enzyme 2

Jiacheng Li, Xiaoliang Ma, Shuai Guo +8

A recent experimental study found that the binding affinity between the cellular receptor human angiotensin converting enzyme 2 (ACE2) and receptor-binding domain (RBD) in spike (S…