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physics.med-ph2021

Label-free virtual Hematoxylin and Eosin (H&E) staining using second generation Photoacoustic Remote Sensing (PARS)

Benjamin R. Ecclestone, Kevan Bell, Sarah Sparkes +3

In the past decades, absorption modalities have emerged as powerful tools for label-free functional and structural imaging of cells and tissues. Many biomolecules present unique ab…

physics.med-ph2021

Three-Dimensional Virtual Histology in Unprocessed Resected Tissues with Photoacoustic Remote Sensing (PARS) Microscopy and Optical Coherence Tomography

Benjamin R. Ecclestone, Zohreh Hosseinaee, Nima Abbasi +4

Histological images are critical in the diagnosis and treatment of cancers. Unfortunately, the current method for capturing these microscopy images require resource intensive tissu…

physics.med-ph2020

Reflection-mode virtual histology using photoacoustic remote sensing microscopy

Kevan Bell, Saad Abbasi, Deepak Dinakaran +5

Histological visualizations are critical to clinical disease management and are fundamental to biological understanding. However, current approaches that rely on bright-field micro…

physics.med-ph2020

Label-free, non-contact, in-vivo ophthalmic imaging using photoacoustic remote sensing microscopy

Zohreh Hosseinaee, Layla Khalili, James Alex Tummon Simmons +2

We present the first label-free, non-contact, in-vivo imaging of the ocular vasculature using photoacoustic remote sensing (PARS) microscopy. Both anterior and posterior segments m…

physics.med-ph2020

Histopathology for Mohs Micrographic Surgery with Photoacoustic Remote Sensing Microscopy

Benjamin R. Ecclestone, Kevan Bell, Saad Abbasi +4

Mohs micrographic surgery (MMS) is a precise oncological technique where layers of tissue are resected and examined with intraoperative histopathology to minimize the removal of no…