Enforcing Thermodynamic Consistency in Parameter Optimization and Bayesian Inference of Biochemical Reaction Networks

Federica Milinanni, Andrei Kramer-Miehe, Jan Glaubitz +1

Subcellular signaling pathways regulating, e.g., cell division or synaptic plasticity, are often modeled as dynamical networks of reactions satisfying the law of mass action. To re…