3 papers
q-bio.QM2026
Agentic Discovery of Non-Canonical Antimicrobial Peptides with AMPGAN v3
Jay Jung, Xiaohan Zhang, Shenghan Song +8
Antimicrobial resistance causes to over a million deaths annually. Antimicrobial peptides (AMPs) are a promising solution, but generative AMP models are not yet ready to design pep…
q-bio.BM2021
Concerted Rolling and Membrane Penetration Revealed by Atomistic Simulations of Antimicrobial Peptides
Jacob M. Remington, Jonathon B. Ferrell, Jianing Li
Short peptides with antimicrobial activity have therapeutic potential for treating bacterial infections. Mechanisms of actions for antimicrobial peptides require binding the biolog…
physics.bio-ph2020
On the Aggregation State of Synergistic Antimicrobial Peptides
Jacob M. Remington, Chenyi Liao, Mona Sharafi +6
By integrating various simulation and experimental techniques, we discovered that antimicrobial peptides (AMPs) may achieve synergy at an optimal concentration and ratio, which can…