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q-bio.QM2022
Pathology Steered Stratification Network for Subtype Identification in Alzheimer's Disease
Enze Xu, Jingwen Zhang, Jiadi Li +4
Alzheimer's disease (AD) is a heterogeneous, multifactorial neurodegenerative disorder characterized by beta-amyloid, pathologic tau, and neurodegeneration. There are no effective…
q-bio.QM2022★ 1 cited
Uncovering the System Vulnerability and Criticality of Human Brain under Dynamical Neuropathological Events in Alzheimer's Disease
Jingwen Zhang, Qing Liu, Haorui Zhang +5
Background: Despite the striking efforts in investigating neurobiological factors behind the acquisition of amyloid-\b{eta} (A), protein tau (T), and neurodegeneration ([N]) biomar…
q-bio.QM2021
Analyzing the Spatiotemporal Interaction and Propagation of ATN Biomarkers in Alzheimer's Disease using Longitudinal Neuroimaging Data
Qing Liu, Defu Yang, Jingwen Zhang +3
Three major biomarkers: beta-amyloid (A), pathologic tau (T), and neurodegeneration (N), are recognized as valid proxies for neuropathologic changes of Alzheimer's disease. While t…