2 papers
cs.LG2025
Cell-ontology guided transcriptome foundation model
Xinyu Yuan, Zhihao Zhan, Zuobai Zhang +5
Transcriptome foundation models TFMs hold great promises of deciphering the transcriptomic language that dictate diverse cell functions by self-supervised learning on large-scale s…
cs.LG2024
Multi-Scale Representation Learning for Protein Fitness Prediction
Zuobai Zhang, Pascal Notin, Yining Huang +5
Designing novel functional proteins crucially depends on accurately modeling their fitness landscape. Given the limited availability of functional annotations from wet-lab experime…