2 papers
q-bio.QM2025
Modeling cell differentiation in neuroblastoma: insights into development, malignancy, and treatment relapse
Simon F. Martina-Perez, Luke A. Heirene, Jennifer C. Kasemeier +2
Neuroblastoma is a paediatric extracranial solid cancer that arises from the developing sympathetic nervous system and is characterised by an abnormal distribution of cell types in…
q-bio.OT2025
An Asymptotic Analysis of Bivalent Monoclonal Antibody-Antigen Binding
Luke A Heirene, Helen M Byrne, James W T Yates +1
Ligand-receptor interactions are fundamental to many biological processes. For example in antibody-based immunotherapies, the dynamics of an antibody binding with its target antige…