2 papers
cs.LG2025
Proteina: Scaling Flow-based Protein Structure Generative Models
Tomas Geffner, Kieran Didi, Zuobai Zhang +8
Recently, diffusion- and flow-based generative models of protein structures have emerged as a powerful tool for de novo protein design. Here, we develop Proteina, a new large-scale…
cs.LG2025
MotifBench: A standardized protein design benchmark for motif-scaffolding problems
Zhuoqi Zheng, Bo Zhang, Kieran Didi +5
The motif-scaffolding problem is a central task in computational protein design: Given the coordinates of atoms in a geometry chosen to confer a desired biochemical function (a mot…