35 citations · 91 across the 5 of their papers we have counts for
5 papers
Charge transport-mediated recruitment of DNA repair enzymes
Pak-Wing Fok, Chin-Lin Guo, Tom Chou
Damaged or mismatched bases in DNA can be repaired by Base Excision Repair (BER) enzymes that replace the defective base. Although the detailed molecular structures of many BER enz…
Non-native beta-sheet formation: insights into protein amyloidosis
Chinlin Guo, Herbert Levine, David A. Kessler
Protein amyloidosis is a cytopathological process characterized by the formation of highly beta-sheet-rich fibrils. How this process occurs and how to prevent/treat the associated…
Mechanisms underlying sequence-independent beta-sheet formation
Chinlin Guo, Herbert Levine, Margaret S. Cheung +1
We investigate the formation of beta-sheet structures in proteins without taking into account specific sequence-dependent hydrophobic interactions. To accomplish this, we introduce…
Two State Behavior in a Solvable Model of -hairpin folding
Chinlin Guo, Herbert Levine, David Kessler
Understanding the mechanism of protein secondary structure formation is an essential part of protein-folding puzzle. Here we describe a simple model for the formation of the -ha…
A Thermodynamic Model for Receptor Clustering
Chinlin Guo, Herbert Levine
Intracellular signaling often arises from ligand-induced oligomerization of cell surface receptors. This oligomerization or clustering process is fundamentally a cooperative behavi…