4 papers
A study of accuracy and precision in oligonucleotide arrays: extracting more signal at large concentrations
Felix Naef, Nicholas D. Socci, Marcelo Magnasco
Despite the success and popularity of oligonucleotide arrays as a high-throughput technique for measuring mRNA expression levels, quantitative calibration studies have until now be…
Unsupervised learning and adaptation in a model of adult neurogenesis
Guillermo A. Cecchi, Leopoldo T. Petreanu, Arturo Alvarez-Buylla +1
Adult neurogenesis has long been documented in the vertebrate brain, and recently even in humans. Although it has been conjectured for many years that its functional role is relate…
From features to expression: High-density oligonucleotide array analysis revisited
Felix Naef, Daniel A. Lim, Nila Patil +1
One of the most popular tools for large scale gene expression studies are high-density oligonucleotide (GeneChip(R)) arrays. These currently have 16-20 small probe cells (``feature…
The thunder of distant Net storms
Marcelo O. Magnasco
Computers and routers on the Internet send each other error messages (called ICMP datagrams) to signal conditions such as network congestion or blackouts. While these datagrams are…