4 papers
Self-construction and destruction of living transport networks
Chanoknun Sintavanuruk, Yoichiro Mori, Reza Farhadifar +1
Biological transport networks adapt through dynamic interactions between material transport and structural modification during growth and development. In this work, we present a mo…
Geometric Effects in Large Scale Intracellular Flows
Olenka Jain, Brato Chakrabarti, Reza Farhadifar +3
This work probes the role of cell geometry in orienting self-organized fluid flows in the late stage Drosophila oocyte. Recent theoretical work has shown that a model, which relies…
A first-principles geometric model for dynamics of motor-driven centrosomal asters
Yuan-Nan Young, Vicente Gomez Herrera, Helena Z. Huan +2
The centrosomal aster is a mobile cellular organelle that exerts and transmits forces necessary for nuclear migration and spindle positioning. Recent experimental and theoretical s…
Mechanics and morphology of proliferating cell collectives with self-inhibiting growth
Scott Weady, Bryce Palmer, Adam Lamson +3
We study the dynamics of proliferating cell collectives whose microscopic constituents' growth is inhibited by macroscopic growth-induced stress. Discrete particle simulations of a…