3 papers
cs.CV2025
Image segmentation of treated and untreated tumor spheroids by Fully Convolutional Networks
Matthias Streller, SoÅa MichlÃková, Willy Ciecior +4
Multicellular tumor spheroids (MCTS) are advanced cell culture systems for assessing the impact of combinatorial radio(chemo)therapy. They exhibit therapeutically relevant in-vivo-…
physics.bio-ph2025
Generalized, sublethal damage-based mathematical approach for improved modeling of clonogenic survival curve flattening upon hyperthermia, radiotherapy, and beyond
Adriana M. De Mendoza, SoÅa MichlÃková, Paula S. Castro +4
Mathematical modeling can offer valuable insights into the behavior of biological systems upon treatment. Different mathematical models have been designed to predict the efficacy o…
q-bio.CB2024
Minimal cellular automaton model with heterogeneous cell sizes predicts epithelial colony growth
Steffen Lange, Jannik Schmied, Paul Willam +1
Regulation of cell proliferation is a crucial aspect of tissue development and homeostasis and plays a major role in morphogenesis, wound healing, and tumor invasion. A phenomenon…