most citedKnowledge-Design: Pushing the Limit of Protein Design via Knowledge Refinement

7 citations · 51 across the 19 of their papers we have counts for

collaborators

19 papers

q-bio.QM2024

Relation-Aware Equivariant Graph Networks for Epitope-Unknown Antibody Design and Specificity Optimization

Lirong Wu, Haitao Lin, Yufei Huang +5

Antibodies are Y-shaped proteins that protect the host by binding to specific antigens, and their binding is mainly determined by the Complementary Determining Regions (CDRs) in th…

cs.DB2024

From Words to Structured Visuals: A Benchmark and Framework for Text-to-Diagram Generation and Editing

Jingxuan Wei, Cheng Tan, Qi Chen +6

We introduce the task of text-to-diagram generation, which focuses on creating structured visual representations directly from textual descriptions. Existing approaches in text-to-…

cs.LG2024

MeToken: Uniform Micro-environment Token Boosts Post-Translational Modification Prediction

Cheng Tan, Zhenxiao Cao, Zhangyang Gao +6

Post-translational modifications (PTMs) profoundly expand the complexity and functionality of the proteome, regulating protein attributes and interactions that are crucial for biol…

q-bio.BM2024

FoldToken2: Learning compact, invariant and generative protein structure language

Zhangyang Gao, Cheng Tan, Stan Z. Li

The equivalent nature of 3D coordinates has posed long term challenges in protein structure representation learning, alignment, and generation. Can we create a compact and invarian…

cs.CL20243 cited

Peer Review as A Multi-Turn and Long-Context Dialogue with Role-Based Interactions

Cheng Tan, Dongxin Lyu, Siyuan Li +5

Large Language Models (LLMs) have demonstrated wide-ranging applications across various fields and have shown significant potential in the academic peer-review process. However, ex…

q-bio.BM20245 cited

FoldToken: Learning Protein Language via Vector Quantization and Beyond

Zhangyang Gao, Cheng Tan, Jue Wang +3

Is there a foreign language describing protein sequences and structures simultaneously? Protein structures, represented by continuous 3D points, have long posed a challenge due to…