2 papers
stat.ME2025
Debiased Estimating Equation Method for Robust and Efficient Mendelian Randomization Using a Large Number of Correlated Weak and Invalid Instruments
Ruoyu Wang, Haoyu Zhang, Xihong Lin
Mendelian randomization (MR) is a widely used tool for causal inference in the presence of unmeasured confounders, which uses single nucleotide polymorphisms (SNPs) as instrumental…
q-bio.MN2024
Genetic studies through the lens of gene networks
Marc Subirana-Granés, Jill Hoffman, Haoyu Zhang +4
Understanding the genetic basis of complex traits is a longstanding challenge in the field of genomics. Genome-wide association studies (GWAS) have identified thousands of variant-…