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4 papers

q-bio.TO2026

TRAECR: A Tool for Preprocessing Positron Emission Tomography Imaging for Statistical Modeling

Akhil Ambekar, Robert Zielinski, Ani Eloyan

The paper introduces TRAECR, a software tool that streamlines preprocessing of PET brain images—including registration, MRI‑PET co‑registration, brain extraction, and intensity har…

stat.ME2026

Causal Inference for Unobservable Multivariate Outcomes, with Applications to Brain Effective Connectivity

Haiyue Song, Ani Eloyan, Youjin Lee

Evaluating the causal effect of an intervention on multivariate outcomes is challenging when the outcomes are interdependent and derived rather than directly observed. Effective co…

stat.AP2025

Geometric Modeling of Hippocampal Tau Deposition: A Surface-Based Framework for Covariate Analysis and Off-Target Contamination Detection

Liangkang Wang, Akhil Ambekar, Ani Eloyan

We introduce a framework combining geometric modeling with disease progression analysis to investigate tau deposition in Alzheimer's disease (AD) using positron emission tomography…

stat.AP2025

Leveraging population information in brain connectivity via Bayesian ICA with a novel informative prior for correlation matrices

Amanda Mejia, David Bolin, Daniel Spencer +1

Brain functional connectivity (FC), the temporal synchrony between brain networks, is essential to understand the functional organization of the brain and to identify changes due t…