3 papers
q-bio.BM2025
AutoLoop: a novel autoregressive deep learning method for protein loop prediction with high accuracy
Tianyue Wang, Xujun Zhang, Langcheng Wang +12
Protein structure prediction is a critical and longstanding challenge in biology, garnering widespread interest due to its significance in understanding biological processes. A par…
q-bio.BM2025
Collaborative Expert LLMs Guided Multi-Objective Molecular Optimization
Jiajun Yu, Yizhen Zheng, Huan Yee Koh +3
Molecular optimization is a crucial yet complex and time-intensive process that often acts as a bottleneck for drug development. Traditional methods rely heavily on trial and error…
q-bio.BM2025
Discovery of novel antimicrobial peptides with notable antibacterial potency by a LLM-based foundation model
Jike Wang, Jianwen Feng, Yu Kang +16
Large language models (LLMs) have shown remarkable advancements in chemistry and biomedical research, acting as versatile foundation models for various tasks. We introduce AMP-Desi…