2 papers
stat.ME2025
A Unified Approach to Covariate Adjustment for Survival Endpoints in Randomized Clinical Trials
Zhiwei Zhang, Ya Wang, Dong Xi
Covariate adjustment aims to improve the statistical efficiency of randomized trials by incorporating information from baseline covariates. Popular methods for covariate adjustment…
stat.ME2024
Futility analyses for the MCP-Mod methodology based on longitudinal models
Björn Bornkamp, Jie Zhou, Dong Xi +1
This article discusses futility analyses for the MCP-Mod methodology. Formulas are derived for calculating predictive and conditional power for MCP-Mod, which also cover the case w…