From the 1 of 4 linked papers with an AI index.
4 papers
Higher-Order Hit-&-Run Samplers for Linearly Constrained Densities
Richard D. Paul, Anton Stratmann, Johann F. Jadebeck +4
The paper introduces a new MCMC algorithm that combines higher‑order information (gradients and curvature of the log‑density) with Hit‑and‑Run proposals to efficiently sample distr…
Automated multi-dataset INST C metabolic flux analysis at microliter scale reveals robust fluxes but variable metabolite pools in
Jochen NieÃer, Anton Stratmann, Martin Beyà +3
Isotopically non-stationary metabolic flux analysis (INST C-MFA) provides unique insights into cellular physiology but is typically limited by low throughput and high experi…
Trans-dimensional Bayesian model averaging for C-based metabolic flux analysis: Evidence-based flux inference under structural model uncertainty
Johann F. Jadebeck, Anton Stratmann, Martin Beyà +1
Accurate quantification of intracellular metabolic fluxes is central to systems biology and biotechnology. Flux estimation relies on biochemical network models, with C metab…
13CFLUX -- Third-generation high-performance engine for isotopically (non)stationary 13C metabolic flux analysis
Anton Stratmann, Martin BeyÃ, Johann F. Jadebeck +2
13C-based metabolic flux analysis (13C-MFA) is a cornerstone of quantitative systems biology, yet its increasing data complexity and methodological diversity place high demands on…