223 citations · 1.1k across the 37 of their papers we have counts for
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T cell morphodynamics reveal periodic shape oscillations in 3D migration
Henry Cavanagh, Daryan Kempe, Jessica K. Mazalo +2
T cells use sophisticated shape dynamics (morphodynamics) to migrate towards and neutralise infected and cancerous cells. However, there is limited quantitative understanding of th…
Physics-Informed Deep Learning Characterizes Morphodynamics of Asian Soybean Rust Disease
Henry Cavanagh, Andreas Mosbach, Gabriel Scalliet +2
Medicines and agricultural biocides are often discovered using large phenotypic screens across hundreds of compounds, where visible effects of whole organisms are compared to gauge…
Thermodynamics of switching in multistable non-equilibrium systems
Jacob Cook, Robert G. Endres
Multistable non-equilibrium systems are abundant outcomes of nonlinear dynamics with feedback but still relatively little is known about what determines the stability of the steady…
Know the single-receptor sensing limit? Think again
Gerardo Aquino, Ned S. Wingreen, Robert G. Endres
How cells reliably infer information about their environment is a fundamentally important question. While sensing and signaling generally start with cell-surface receptors, the deg…
Memory improves precision of cell sensing in fluctuating environments
Gerardo Aquino, Luke Tweedy, Doris Heinrich +1
Biological cells are often found to sense their chemical environment near the single-molecule detection limit. Surprisingly, this precision is higher than simple estimates of the f…
Optimal receptor-cluster size determined by intrinsic and extrinsic noise
Gerardo Aquino, Diana Clausznitzer, Sylvain Tollis +1
Biological cells sense external chemical stimuli in their environment using cell-surface receptors. To increase the sensitivity of sensing, receptors often cluster, most noticeably…