activity
20232025
most citedOptimal allocation strategies in platform trials

6 citations · 13 across the 5 of their papers we have counts for

collaborators

5 papers

stat.ME2025

On the inclusion of non-concurrent controls in platform trials with an interim analysis

Pavla Krotka, Martin Posch, Marta Bofill Roig

The analysis of platform trials can be enhanced by utilizing non-concurrent controls. Since including this data might also introduce bias in the treatment effect estimators if time…

stat.ME2024★ 2 cited

Treatment-control comparisons in platform trials including non-concurrent controls

Marta Bofill Roig, Pavla Krotka, Katharina Hees +5

Shared controls in platform trials comprise concurrent and non-concurrent controls. For a given experimental arm, non-concurrent controls refer to data from patients allocated to t…

stat.ME2024★ 4 cited

Statistical modeling to adjust for time trends in adaptive platform trials utilizing non-concurrent controls

Pavla Krotka, Martin Posch, Mohamed Gewily +2

Utilizing non-concurrent control data (NCC) in the analysis of late-entering arms in platform trials has recently received considerable attention. While incorporating NCC can lead…

stat.ME2023★ 6 cited

Optimal allocation strategies in platform trials

Marta Bofill Roig, Ekkehard Glimm, Tobias Mielke +1

Platform trials are randomized clinical trials that allow simultaneous comparison of multiple interventions, usually against a common control. Arms to test experimental interventio…

stat.ME2023★ 1 cited

ADDIS-Graphs for online error control with application to platform trials

Lasse Fischer, Marta Bofill Roig, Werner Brannath

In contemporary research, online error control is often required, where an error criterion, such as familywise error rate (FWER) or false discovery rate (FDR), shall remain under c…