2 papers
q-bio.BM2025
Differentiable Folding for Nearest Neighbor Model Optimization
Ryan K. Krueger, Sharon Aviran, David H. Mathews +2
The Nearest Neighbor model is the thermodynamic model of RNA secondary structure formation and is a cornerstone of RNA structure prediction and sequence design.…
q-bio.BM2025
mRNA Folding Algorithms for Structure and Codon Optimization
Max Ward, Mary Richardson, Mihir Metkar
mRNA technology has revolutionized vaccine development, protein replacement therapies, and cancer immunotherapies, offering rapid production and precise control over sequence and e…