most citedPredicting drug-target interaction using 3D structure-embedded graph representations from graph neural networks

5 citations · 5 across the 1 of their papers we have counts for

collaborators

5 papers

physics.chem-ph2019

Molecular Generative Model Based On Adversarially Regularized Autoencoder

Seung Hwan Hong, Jaechang Lim, Seongok Ryu +1

Deep generative models are attracting great attention as a new promising approach for molecular design. All models reported so far are based on either variational autoencoder (VAE)…

cs.LG2019

Scaffold-based molecular design using graph generative model

Jaechang Lim, Sang-Yeon Hwang, Seungsu Kim +2

Searching new molecules in areas like drug discovery often starts from the core structures of candidate molecules to optimize the properties of interest. The way as such has called…

cs.LG20195 cited

Predicting drug-target interaction using 3D structure-embedded graph representations from graph neural networks

Jaechang Lim, Seongok Ryu, Kyubyong Park +3

Accurate prediction of drug-target interaction (DTI) is essential for in silico drug design. For the purpose, we propose a novel approach for predicting DTI using a GNN that direct…

cs.LG2018

Molecular generative model based on conditional variational autoencoder for de novo molecular design

Jaechang Lim, Seongok Ryu, Jin Woo Kim +1

We propose a molecular generative model based on the conditional variational autoencoder for de novo molecular design. It is specialized to control multiple molecular properties si…

cs.LG2018

Deeply learning molecular structure-property relationships using attention- and gate-augmented graph convolutional network

Seongok Ryu, Jaechang Lim, Seung Hwan Hong +1

Molecular structure-property relationships are key to molecular engineering for materials and drug discovery. The rise of deep learning offers a new viable solution to elucidate th…