4 papers
Extracellular Matrix regulates the morphodynamics of 3D migrating cancer cells
Christopher Z. Eddy, Helena Raposo, Ryan Wong +1
Cell shape is linked to cell function. The significance of cell morphodynamics, namely the temporal fluctuation of cell shape, is much less understood. Here we study the morphodyna…
Modeling Multi-Cellular Dynamics Regulated by ECM-Mediated Mechanical Communication via Active Particles with Polarized Effective Attraction
Yu Zheng, Qihui Fan, Christopher Eddy +4
Collective cell migration is crucial to many physiological and pathological processes. Recent experimental studies have indicated that the active traction forces generated by migra…
Collective dynamics and self-organization of active particles on random networks
Hanqing Nan, Yu Zheng, Shaohua Chen +5
Collective cell migration in 3D extracellular matrix (ECM) is crucial to many physiological and pathological processes. Migrating cells can generate active pulling forces via actin…
The morphodynamics of 3D migrating cancer cells
Christopher Z. Eddy, Xinyao Wang, Fuxin Li +1
Cell shape is an important biomarker that is directly linked to cell function. However, cell morphodynamics, namely the temporal fluctuation of cell shape is much less understood.…