3 papers
q-bio.PE2025
Synergistic interplay of morphology and metabolic activity rule response to CAR-T cells in B-cell lymphomas
Yifan Chen, Soukaina Sabir, Christina Kuttler +13
Cellular immunotherapies are one of the mainstream cancer treatments unveiling the power of the patient's immune system to fight tumors. CAR T-cell therapy, based on genetically en…
q-bio.TO2025
Geometric immunosuppression in CAR-T cell treatment: Insights from mathematical modeling
Silvia Bordel-Vozmediano, Soukaina Sabir, LucÃa Benito-Barca +2
Chimeric antigen receptor T (CAR-T) cell therapy has emerged as a promising treatment for hematological malignancies, offering a targeted approach to cancer treatment. Understandin…
q-bio.PE2024
Mathematical model of CAR-T-cell therapy for a B-cell Lymphoma lymph node
Soukaina Sabir, Odelaisy León-Triana, Sergio Serrano +2
CAR-T cell therapies have demonstrated significant success in treating B-cell leukemia in children and young adults. However, their effectiveness in treating B-cell lymphomas has b…