3 papers
q-bio.GN2019
Genome analysis and pleiotropy assessment using causal networks with loss of function mutation and metabolomics
Azam Yazdani, Akram Yazdani, Sarah H. Elsea +4
Background: Many genome-wide association studies have detected genomic regions associated with traits, yet understanding the functional causes of association often remains elusive.…
q-bio.GN2018
Integrated systems approach identifies pathways from the genome to triglycerides through a metabolomic causal network
Azam Yazdani, Akram Yazdani, Philip L. Lorenzi +1
Introduction: To leverage functionality and clinical relevance into understanding systems biology, one needs to understand the pathway of the genetic effects on risk factors/diseas…
q-bio.GN2018
Insights into Complex Brain Functions Related to Schizophrenia Disorder through Causal Network Analysis
Akram Yazdani, Raul Mendez Giraldez, Ahmad Samiei
Gene expression represents a fundamental interface between genes and environment in the development and ongoing plasticity of the human organism. Individual differences in gene exp…