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researcher

P. Bourne

4 papers hereh-index 7036.1k citations410 works total

Matching runs newest-first, so older work may not be attached to this profile yet.

author position
  • last author4

Across the 4 of 4 papers where every author was matched, so the position is known.

fields
  • q-bio.BM2
  • q-bio.MN2

identity via Semantic Scholar / OpenAlex

activity
20182020
most citedStructural insights into characterizing binding sites in EGFR kinase mutants

57 citations · 58 across the 3 of their papers we have counts for

collaborators

4 papers

q-bio.BM2020

Deep Learning of Protein Structural Classes: Any Evidence for an 'Urfold'?

Menuka Jaiswal, Saad Saleem, Yonghyeon Kweon +4

Recent computational advances in the accurate prediction of protein three-dimensional (3D) structures from amino acid sequences now present a unique opportunity to decipher the int…

q-bio.BM2019★ 1 cited

Machine Learning for Classification of Protein Helix Capping Motifs

Sean Mullane, Ruoyan Chen, Sri Vaishnavi Vemulapalli +4

The biological function of a protein stems from its 3-dimensional structure, which is thermodynamically determined by the energetics of interatomic forces between its amino acid bu…

q-bio.MN2018★ 57 cited

Structural insights into characterizing binding sites in EGFR kinase mutants

Zheng Zhao, Lei Xie, Philip E. Bourne

Over the last two decades epidermal growth factor receptor (EGFR) kinase has become an important target to treat non-small cell lung cancer (NSCLC). Currently, three generations of…

q-bio.MN2018

Overview of Current Type I/II Kinase Inhibitors

Zheng Zhao, Philip E. Bourne

Research on kinase-targeting drugs has made great strides over the last 30 years and is attracting greater attention for the treatment of yet more kinase-related diseases. Currentl…

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