3 papers
q-bio.QM2020
Push-forward method for piecewise deterministic biochemical simulations
Guilherme C. P. Innocentini, Arran Hodgkinson, Fernando Antoneli +2
A biochemical network can be simulated by a set of ordinary differential equations (ODE) under well stirred reactor conditions, for large numbers of molecules, and frequent reactio…
q-bio.MN2019
Effective computational methods for hybrid stochastic gene networks
Guilherme C. P. Innocentini, Fernando Antoneli, Arran Hodgkinson +1
At the scale of the individual cell, protein production is a stochastic process with multiple time scales, combining quick and slow random steps with discontinuous and smooth varia…
q-bio.CB2018
Signal propagation in sensing and reciprocating cellular systems with spatial and structural heterogeneity
Arran Hodgkinson, Giles Uzé, Ovidiu Radulescu +1
Sensing and reciprocating cellular systems (SARs) are important for the operation of many biological systems. Production in interferon (IFN) SARs is achieved through activation of…