11 citations · 25 across the 12 of their papers we have counts for
14 papers
An open-source computational framework for immersed fluid-structure interaction modeling using FEBio and MFEM
Ryan T. Black, Steve A. Maas, Wensi Wu +4
Fluid-structure interaction (FSI) simulation of biological systems presents significant computational challenges, particularly for applications involving large structural deformati…
Effect of Right Ventricular Outflow Tract Material Properties on Simulated Transcatheter Pulmonary Placement
Jalaj Maheshwari, Wensi Wu, Christopher N. Zelonis +9
FE simulations emulating TPV system deployment in patient-specific right ventricular outflow tracts (RVOT) assume material properties for the RVOT and adjacent tissues. Sensitivity…
Simulation of Transcatheter Therapies for Atrioventricular Valve Regurgitation in an Open-Source Finite Element Simulation Framework
Seda Aslan, Nicolas R. Mangine, Devin W. Laurence +8
Purpose: Transcatheter edge-to-edge repair (TEER) and annuloplasty devices are increasingly used to treat mitral valve regurgitation, yet their mechanical effects and interactions…
Simulation of Repair on Dynamic Patient-Specific Left Atrioventricular Valve Models
Stephen Ching, Christopher Zelonis, Christian Herz +12
Purpose: To develop and evaluate a dynamic, image-derived patient-specific physical simulation platform for the assessment of left atrioventricular valve (LAVV) repair strategies i…
Integrated Open-Source Framework for Simulation of Transcatheter Pulmonary Valves in Native Right Ventricular Outflow Tracts
Christopher N. Zelonis, Jalaj Maheshwari, Wensi Wu +14
Pulmonary insufficiency is a consequence of transannular patch repair in Tetralogy of Fallot (ToF), leading to late morbidity and mortality. Transcatheter native outflow tract pulm…
Effect of Parametric Variation of Chordae Tendineae Structure on Simulated Atrioventricular Valve Closure
Nicolas R. Mangine, Devin W. Laurence, Patricia M. Sabin +9
Many approaches have been used to model chordae tendineae geometries in finite element simulations of atrioventricular heart valves. Unfortunately, current "functional" chordae ten…
ADEPT: A Noninvasive Method for Determining Elastic Parameters of Valve Tissue
Wensi Wu, Mitchell Daneker, Christian Herz +5
Computer simulation of "virtual interventions" may inform optimal valve repair for a given patient prior to intervention. However, the paucity of noninvasive methods to determine i…
FEBio FINESSE: An open-source finite element simulation approach to estimate in vivo heart valve strains using shape enforcement
Devin W. Laurence, Patricia M. Sabin, Analise M. Sulentic +4
Finite element simulations are an enticing tool to evaluate heart valve function in healthy and diseased patients; however, patient-specific simulations derived from 3D echocardiog…
Geodesic-based Predictive Shape Modeling of the Right Ventricle in Patients with Hypoplastic Left Heart Syndrome
Ye Han, James Fishbaugh, Jared Vicory +9
Hypoplastic left heart syndrome (HLHS) is characterized by severe underdevelopment of left ventricle requiring staged surgical reconstruction (stages) to allow the right ventricle…
Identifying heterogeneous micromechanical properties of biological tissues via physics-informed neural networks
Wensi Wu, Mitchell Daneker, Kevin T. Turner +2
The heterogeneous micromechanical properties of biological tissues have profound implications across diverse medical and engineering domains. However, identifying full-field hetero…
The effects of leaflet material properties on the simulated function of regurgitant mitral valves
Wensi Wu, Stephen Ching, Patricia Sabin +5
Advances in three-dimensional imaging provide the ability to construct and analyze finite element (FE) models to evaluate the biomechanical behavior and function of atrioventricula…
Effective Data Sampling Strategies and Boundary Condition Constraints of Physics-Informed Neural Networks for Identifying Material Properties in Solid Mechanics
Wensi Wu, Mitchell Daneker, Matthew A. Jolley +2
Material identification is critical for understanding the relationship between mechanical properties and the associated mechanical functions. However, material identification is a…
A Computational Framework for Atrioventricular Valve Modeling using Open-Source Software
Wensi Wu, Stephen Ching, Steve A. Maas +4
Atrioventricular valve regurgitation is a significant cause of morbidity and mortality in patients with acquired and congenital cardiac valve disease. Image-derived computational m…
Interactive-Automatic Segmentation and Modelling of the Mitral Valve
Patrick Carnahan, Olivia Ginty, John Moore +6
Mitral valve regurgitation is the most common valvular disease, affecting 10% of the population over 75 years old. Left untreated, patients with mitral valve regurgitation can suff…